Poly-PLUS is a scientifically formulated supplement containing Poly MVA and vitamin A. Poly MVA contains a Lipoic Acid Mineral Complex (LAMC) which is composed of the transition element palladium covalently bound to the antioxidant alpha-lipoic acid, creating a potent redox polymer. A redox molecule not only absorbs electrons, but it also donates them. In addition to bound Palladium-Lipoic Acid, the proprietary formulation also contains thiamine, riboflavin, cyanocobalamin, formyl-methionine, N acetyl-cysteine and vitamin A. Vitamin A works synergistically with the LAMC formulation to further potentiate aerobic metabolism.
Since the lipoic acid and thiamine cofactors in the LAMC formulation act early in the aerobic cascade, they show the direct its benefit to the mitochondria.
With age, there is a decrease in the ability of body tissues to produce energy, an increase in the production of harmful free radicals, and a decrease in the number of anti-oxidants. Sudheesh et al. (2009, 2010, 2014) have demonstrated that the LAMC formulation not only enhances aerobic metabolism by statistically increasing the enzymatic activity of the Krebs’s Cycle and Electron Transport Chain, but potentiates the quenching of free radicals by elevating anti-oxidant levels in tissues.
In addition to vitamin A’s benefits to the skin, immune system and vision a recent study has demonstrated its enhanced energy benefit to LAMC. In a pre-clinical model of radiation-induced hematological anemia, the addition of vitamin A to the LAMC formulation significantly enhanced hemoglobin content and red blood cell counts, while maintaining LAMC’s anti-oxidant benefit. Additional work has demonstrated that a reduction in vitamin A reduced cellular respiration and ATP production. Therefore, vitamin A’s ability to potentiate oxygen delivery makes it synergistic with LAMC in Poly-PLUS.
In 2009 LAMC formulation was granted, from the FDA, an IND and has completed a Phase I dose-escalation safety at Stony Brook University.
In summary, Poly-PLUS is an enhanced version of the LAMC formulation which can be utilized to potentiate cellular energy, attenuate fatigue and support therapy of metabolically dysfunctional neoplastic tissue.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.